Freeze-drying (also known as lyophilisation, lyophilization, or cryodesiccation) is a dehydration process. It’s typically used in the Pharmaceutical, Biotech, Food, and Agriculture-based industries to increase shelf life, preserve structural and chemical integrity/composition, and or make a material more convenient for transport. A freeze-dryer is a device that uses this dehydration process to freeze a material and then reduce the surrounding pressure to allow the frozen water in the material to sublimate directly from the solid phase to the gas phase.
There are three categories of Freeze-Dryers: the manifold freeze-dryer, the rotary freeze-dryer, and the tray style freeze-dryer. There are two components that are the same in all three types: a vacuum pump to reduce gas pressure, and a condenser to remove the moisture by condensation. The three different types of freeze-dryers differ in method by which the dried substance is interfaced with a condenser.
Rotary freeze-dryers are usually used for drying pellets, cubes and other pourable substances. The rotary dryers have a cylindrical reservoir that is rotated during drying to achieve a more uniform drying throughout the substance. Manifold freeze-dryers are usually used in a laboratory setting when drying liquid substances in small containers and when the product will be used in a short period of time. Tray style freeze-dryers are typically larger than the manifold dryers and are more sophisticated. Tray style freeze-dryers are used to dry a variety of materials. A tray freeze-dryer is used to produce the driest product for long-term storage.
Top Freeze Dryer Equipment Manufacturers
HiTechTrader offers a variety of freeze-dryers. Labconco and MillRock Technology are excellent manufacturers.
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