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In House Potency Testing: Why a Used Agilent HPLC Can Beat Outsourcing

The outsourcing dilemma in cannabis labs

Many cannabis operators start by outsourcing potency testing to third-party labs. It makes sense early on, but as volume grows, outsourcing can create:

• turnaround delays
• recurring testing costs
• limited process visibility
• batch release bottlenecks

That’s why many mid-scale operators explore in-house HPLC testing, often using proven platforms like used Agilent systems.

Why potency testing is operationally critical

Potency data affects:

• product labeling
• compliance
• batch release timing
• formulation adjustments
• pricing tiers

Waiting days for third-party results can slow production decisions.

The cost math: outsourcing vs owning

Outsourcing costs add up

If you test:

• multiple batches per week
• multiple SKUs
• stability samples

Monthly testing spend can become substantial.

In-house HPLC costs are mostly upfront

A used HPLC investment includes:

• instrument cost
• setup and validation
• training and consumables

But once running, per-test costs often drop significantly compared to outsourcing.

Speed advantage: control your own timelines

In-house testing allows:

• same-day potency data
• rapid process adjustments
• faster batch release
• better R&D iteration speed

For high-volume extraction, time savings alone can justify the investment.

Why used HPLC platforms are popular in cannabis labs

Many cannabis labs choose used systems because:

• lower capital barrier
• proven performance
• widely understood workflows
• available parts and service ecosystems

Platforms like Agilent HPLC systems are commonly selected due to familiarity and support networks (availability varies by region and supplier).

What you need beyond the instrument

Buying an HPLC isn’t just hardware. Plan for:

• columns and consumables
• standards and calibration materials
• solvent management
• trained analysts
• method validation appropriate to your use case

A realistic implementation plan ensures smooth adoption.

When outsourcing still makes sense

Outsourcing may remain useful for:

• confirmatory testing
• regulated certification requirements
• overflow capacity
• early-stage operators with low volume

Many labs run a hybrid model. Explore our inventory.

FAQ

Do I need a full compliance lab to run in-house potency testing?
Requirements vary by jurisdiction and business model. Always align with local regulations and intended use of results.

Is used HPLC reliable enough?
Reliability depends on refurbishment quality, maintenance, and proper setup—not just age.

Speak with an expert
Tell HiTechTrader your testing volume, turnaround needs, and budget. We can help you evaluate whether a used HPLC makes financial and operational sense for your cannabis operation. Click here to contact HiTechTrader.